Mouse Strains

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Obligatory rules for use of mouse strains within the GRK

The use of animals for experiments is strictly regulated. Hence the following rules have to be strictly applied.

Obtaining govermental approval of the experimental protocol. This protocol has to be submitted to the animal welfare representative of the University, who comments and forwards the protocol to the respective govermental administration. There the proposals are reviewed by scientists and representatives from animal welfare organisations. This comission gives a recommendation on the protcol, and based on this recommendation, the govermental administration takes the decision. 

If you have obtained the respective approval of your protocol, the commercially available mice can be shared only within the GRK. Distribution of these mice outside of the GRK is strickly forbidden by regulations from the suppliers. 

Mouse strains that are provided by scientists outside the GRK to individual researchers can only be used if a material transfer agreement (MTA) with the providing institution has been made. The MTA limits the use of these mice to agreed projects, to ensure that the intellectual rights of the person who generated the mouse line are protected. 

Mouse strains generated within the GRK, can be used by all GRK researchers. You find a list of available strains below:

Department of Dermatology, University Hospital Schleswig-Holstein, Campus Kiel  - research group Karina Reiß

B6-SPP

Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel  - research group Philip Rosenstiel

Atg16l1 Vil-Cre conditional Knockout
Dlg5 Vil-Cre conditional Knockout
IL6R Vil-Cre conditional Knockout
Nlrc5 constitutive Knockout
NOD2 constitutive Knockout, Jax Lab Stock 5763
NOD2 SNP13 Knockin 
Ormdl3 constitutive Knockout
IL23R Vil-Cre conditional Knockout
Lgr5-EGFP-IRES-creERT2 ROSA26 LacZ, Jax Lab - Stock 8875 crossed with Rosa26 LacZ

 

Lübeck Institute of Experimental Dermatology, University Hospital Schleswig-Holstein, Campus Lübeck

B10.D2-Hc0(C5 KO on C57BL/10Sn background)
B10.D2-Hc1(C5 suficient on C57BL/10Snbackground)
B6-Ccr2
B6-CD44
B6.c-mpl
B6-C3
B6-C5ar backcrossed to the B6 background by Prof. Köhl
B6-C5L2
B6-Fcer1g
B6-Fcgr2b
B6-Foxn1 (B6 nude)
B6.Gm-csf
B6-IL10 reporter
B6-Il1alpha/beta
B6-Il1beta 
B6-Ucp2
BALB/c nude
BcN/LmoJ
DEREG (on B6 background)
Lys-EGFP-ki
B6.s-Fcer1g
B6.s-Fcgr2b
B6.s-C5aR1
B6-Syk
B6-Cd19 cre
B6-Lyz cre 
B6-H2k
B6-CD2 cre
B6-Vav cre
B6-BLT1
B6-Alox5
B6-Alox15
BALB/c-GATA1
B6-CD45.1
B6-Trem1
B6-FLP deleter
BALB/c-CD1
B6.LyzCre-Sky
B6.CD2Cre-Sky
B6.VavCre-Sky
B6.CD19Cre-Syk
 
Conplastic Strains
 
C57BL/6J-mt129P3/J
C57BL/6J-mt129S1/SVImJ
C57BL/6J-mtAKR/J
C57BL/6J-mtALR/LtJ
C57BL/6J-mtBPL/1J
C57BL/6J-mtBUB/BnJ
C57BL/6J-mtC3H/HeJ
C57BL/6J-mtCAST/EiJ
C57BL/6J-mtFVB/NJ
C57BL/6J-mtKK/HlJ
C57BL/6J-mtMA/MyJ
C57BL/6J-mtMRL/MpJ
C57BL/6J-mtMOLF/EiJ
C57BL/6J-mtNOD/ShiLtJ
C57BL/6J-mtNZB/BlNJ
C57BL/6J-mtPWD/PhJ
 
- DBA/1J-mtAKR/J
- DBA/1J-mtFVB/NJ
- DBA/1J-mtNOD/ShiLtJ
 
- MRL/MpJ-mtC57BL/10SnJ
- MRL/MpJ-mtFVB/NJ
 
- NOD/ShiLtJ-mtFVB/NJ