Obligatory rules for use of mouse strains within the GRK
The use of animals for experiments is strictly regulated. Hence the following rules have to be strictly applied.
Obtaining govermental approval of the experimental protocol. This protocol has to be submitted to the animal welfare representative of the University, who comments and forwards the protocol to the respective govermental administration. There the proposals are reviewed by scientists and representatives from animal welfare organisations. This comission gives a recommendation on the protcol, and based on this recommendation, the govermental administration takes the decision.
If you have obtained the respective approval of your protocol, the commercially available mice can be shared only within the GRK. Distribution of these mice outside of the GRK is strickly forbidden by regulations from the suppliers.
Mouse strains that are provided by scientists outside the GRK to individual researchers can only be used if a material transfer agreement (MTA) with the providing institution has been made. The MTA limits the use of these mice to agreed projects, to ensure that the intellectual rights of the person who generated the mouse line are protected.
Mouse strains generated within the GRK, can be used by all GRK researchers. You find a list of available strains below:
Department of Dermatology, University Hospital Schleswig-Holstein, Campus Kiel - research group Karina Reiß
Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel - research group Philip Rosenstiel
|Atg16l1 Vil-Cre conditional Knockout|
|Dlg5 Vil-Cre conditional Knockout|
|IL6R Vil-Cre conditional Knockout|
|Nlrc5 constitutive Knockout|
|NOD2 constitutive Knockout, Jax Lab Stock 5763|
|NOD2 SNP13 Knockin|
|Ormdl3 constitutive Knockout|
|IL23R Vil-Cre conditional Knockout|
|Lgr5-EGFP-IRES-creERT2 ROSA26 LacZ, Jax Lab - Stock 8875 crossed with Rosa26 LacZ|
Lübeck Institute of Experimental Dermatology, University Hospital Schleswig-Holstein, Campus Lübeck
|B10.D2-Hc0(C5 KO on C57BL/10Sn background)|
|B10.D2-Hc1(C5 suficient on C57BL/10Snbackground)|
|B6-C5ar backcrossed to the B6 background by Prof. Köhl|
|B6-Foxn1 (B6 nude)|
|DEREG (on B6 background)|