Mouse Strains

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Obligatory rules for use of mouse strains within the GRK

The use of animals for experiments is strictly regulated. Hence the following rules have to be strictly applied.

Obtaining govermental approval of the experimental protocol. This protocol has to be submitted to the animal welfare representative of the University, who comments and forwards the protocol to the respective govermental administration. There the proposals are reviewed by scientists and representatives from animal welfare organisations. This comission gives a recommendation on the protcol, and based on this recommendation, the govermental administration takes the decision.

If you have obtained the respective approval of your protocol, the commercially available mice can be shared only within the GRK. Distribution of these mice outside of the GRK is strickly forbidden by regulations from the suppliers.

Mouse strains that are provided by scientists outside the GRK to individual researchers can only be used if a material transfer agreement (MTA) with the providing institution has been made. The MTA limits the use of these mice to agreed projects, to ensure that the intellectual rights of the person who generated the mouse line are protected.

Mouse strains generated within the GRK, can be used by all GRK researchers. You find a list of available strains below:

Department of Dermatology, University Hospital Schleswig-Holstein, Campus Kiel - research group Karina Reiß

B6-SPP

Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel - research group Philip Rosenstiel

Atg16l1 Vil-Cre conditional Knockout

Dlg5 Vil-Cre conditional Knockout

IL6R Vil-Cre conditional Knockout

Nlrc5 constitutive Knockout

NOD2 constitutive Knockout, Jax Lab Stock 5763

NOD2 SNP13 Knockin

Ormdl3 constitutive Knockout

IL23R Vil-Cre conditional Knockout