Update Data Management - Proteogenomics and Immunopeptidomics – Doc’s Talks

25 May, 2020

Due to the ongoing Corona-crisis, the 8th RTG1743 meeting was conducted on the 15 of May 2020 via the online platform Zoom.     

                                                                                         photo: Alexandra Koch, pixabay, 2020

For the doctoral researchers of the RTG 1743 the meeting started with a talk of Dr. Johannes Labrenz, Quality Assurance Manager of the Cluster of Excellence Precision Medicine in Chronic Inflammation PMI. He informed about the rising requirements for well-conceived data management and helpful rules like: Findable, Accessible, Interoperable and Reusable. He further described the data-management infrastructure provided by the University of Kiel.

Prof. Franke, the spokesperson of the RTG 1743, updated all RTG1743 members afterward about the current “Corona” situation and its impact on doctoral researcher´s life and their research projects. This was followed by an active discussion that addressed concerns and questions of the junior scientists. Next, Prof. Franke gave an overview of the winning projects of the RTG1743 Research Training Group Mini-Proposals 2020.

In the first “talks session” two medical-doctorate researchers, Anna Schaade and Martin Amendt, gave an introductory talk about themselves and their project. Afterward, the two junior scientists Adina-Malin Tietje and Hesham ElAbd updated all RTG members about the recent findings in their project. Adina introduced her multi-omic approach to characterize host-microbial interaction, while Hesham, introduced his AI-powered pipeline for predicting peptide-HLA interactions.  

After a short virtual coffee break, the guest keynote speaker Prof. Dr. Michal Bassani-Sternberg from Ludwig Cancer Research, University of Lausanne (Switzerland) presented her recent work regarding Proteogenomics and Immunopeptidomics. She illustrated how the power of immunopeptidomics, next-generation sequencing and bioinformatics can be combined to yield better immunotherapies. The talk was followed by an active discussion about how the current limitations of immunopeptidomics and possible future direction to improve the accuracy, sensitivity and reproducibility of the technology. For this part of the meeting, several doctoral researchers from other RTGs in Kiel and Lübeck joined.

Dora Bordoni and Hesham El Abd