Elisa Rosati

Consolidated Researcher Details:

Institute:
Institute of Clinical Molecular Biology, Kiel University
Website:
Institute of Clinical Molecular Biology
Dr. rer. nat.
Elisa Rosati
e.rosati [at] ikmb.uni-kiel.de
+49 (0) 431 / 500 - 15 164
RTG-Project (Associated Scientist): NextGen Immunology: Modeling microbial HLA-II peptidomes and identification of disease-relevant T cell epitopes using artificial intelligence and immunopeptidomics
RTG-Project (Associated Scientist): Immune repertoire longitudinal analyses in breast cancer during immunochemotherapy
RTG-Project (Associated Scientist): Defining disease-associated T and B cell repertoires in chronic inflammatory bowel diseases
Publications: Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associations.
Publications: Identification of disease-associated traits and clonotypes in the T-cell receptor repertoire of monozygotic twins affected by inflammatory bowel diseases.
Publications: Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells and plasmablasts as hallmarks of severe COVID-19 trajectories.
Publications: Low avidity CD4+ T cell responses to SARS-CoV-2 in unexposed individuals and humans with severe COVID-19.
Publications: Construction and Benchmarking of a Multi-Ethnic Reference Panel for the Imputation of HLA Class I and II Alleles
Publications: Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease
Publications: Overview of methodologies for T-cell receptor repertoire analysis.

Why this profession?

Many questions in medicine and biology still don’t have an answer. This is one of the main reasons why I decided to study biology, because I liked the idea of discovering something new and of a life dedicated to a continuous learning process. In particular, I choose molecular biology, curious to find out more about the “extremely small” part of biology. While I was studying my interest grew up with me and it focused on more specific topics. One of these is the immune system. Its capacity to protect the organism from external and internal threats always seemed impressive to me, so I was looking forward to work with it a bit more in detail and I am glad I have been given this possibility here in the Institute of Clinical Molecular Biology.

Why RTG Genes, Environment and Inflammation?

I always considered collaboration a milestone of the scientist job. Learning about the fascinating topic of inflammation, directly from and with people which carry on research on various aspects of the topic, is a great opportunity. The RTG “Genes, Environment and Inflammation” allow both a collaborative and information-sharing environment combined with focused young scientists training which, together, form a powerful alliance.