Hauke Stephan Busch

Consolidated Researcher Details:

Lübeck Institute of Experimental Dermatology, University of Lübeck
Research Area:
System Biology of Inflammatory Diseases
Prof. Dr. rer. nat.
Hauke Stephan Busch
hauke.busch [at] uni-luebeck.de
+49 (0) 451 / 31 01 - 84 70

Why this profession?

At the end of my studies in Physics, I came across Biology for the first time and I have never left the field since. I was intrigued by translating principles of complex systems to biology. Those systems are characterised by mesoscopic scales, heterogenous components and exchange of energy with the environment all of which allow the emergence of intricate structures and dynamics far from thermodynamic equilibrium. Understanding all details of the feedback-regulated molecular mechanisms between genes, environment and inflammation in living systems will be an ongoing task for years to come. Yet, the combination of ideas from systems theory with the rapidly emerging sequencing technologies and computational powers will allow ever deeper and more profound insights into this field of biology and medicine, and principles of life in general, which keeps this profession interesting throughout the years.

Why RTG Genes, Environment and Inflammation?

The reach of this RTG from monogenetic diseases to complex multi-variate gene-environment interaction is enormous. And so are the challenges.

Inflammatory processes are virtually everywhere, from pathogen induced infection, autoimmunity to cancer. Understanding how our body balances and manages the immune system is intriguing and ever more interesting, as I have engaged in this field only recently since my move to Lübeck in 2016.