1127: Epithelial CGAS/STING Guides DNA Damage-driven Stem Cell Function and protect from Intestinal Carcinogenesis

Title of publication: 

1127: Epithelial CGAS/STING Guides DNA Damage-driven Stem Cell Function and protect from Intestinal Carcinogenesis

Authors: 

Hang Xiang, Gabriela Rios Martini, Felix Wottawa, Joana P. Bernardes, Björn Konukiewitz, Florian Tran, Nassim H. Kakavand, Qicong Wu, Julia Kugler, Lina Welz, Philip Rosenstiel, Konrad Aden

Year of Publication: 

2022

medium resp. publishing house / place: 

Gastroenterology

edition / issue: 

May, 162

Pages: 

7, Supplement; S-262

related to project: 

Role of ATG16L1 in coordinating DNA damage induced inflammation and tumorigenesis in the intestinal epithelium
Endoplasmic reticulum stress in IBD – key regulator of innate immune signalling?
Role of the ER stress protein XBP-1 in coordinating DNA damage induced inflammation and tumorigenesis in the intestinal epithelium
Characterization of microbe-specific T cell response in Inflammatory Bowel Disease

Pubmed: 

DOI: https://doi.org/10.1016/S0016-5085(22)60621-8