Extracellular sphingomyelinase activity impairs TNF-α-induced endothelial cell death via ADAM17 activation and TNF receptor 1 shedding

Title of publication: 

Extracellular sphingomyelinase activity impairs TNF-α-induced endothelial cell death via ADAM17 activation and TNF receptor 1 shedding

Authors: 

Anselm Sommer, Marie Düppe, Lena Baumecker, Felix Kordowski, Joscha Büch, Johaiber Fuchslocher Chico, Jürgen Fritsch, Stefan Schütze, Dieter Adam, Maria Sperrhacke, Sucharit Bhakdi, Karina Reiss.

Year of Publication: 

2017

medium resp. publishing house / place: 

Oncotarget

edition / issue: 

8(42)

Pages: 

72584–72596

related to project: 

Influence of environmental factors on the regulation of the metalloproteases ADAM10 and ADAM17
Influence of environmental factors on ADAM activity with regard to inflammatory diseases such as Alzheimer`s disease

Pubmed: 

Pubmed - PMID PMC5641154