Publications
The intracellular proteome of the gut bacterium Bacteroides thetaiotaomicron is widely unaffected by a switch from glucose to sucrose as main carbohydrate source
(2022)
The intracellular proteome of the gut bacterium Bacteroides thetaiotaomicron is widely unaffected by a switch from glucose to sucrose as main carbohydrate source
Proteomics
Jul 29;e2200189
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
(2022)
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
Hum Mol Genet.
Jul 15:ddac158:
1127: Epithelial CGAS/STING Guides DNA Damage-driven Stem Cell Function and protect from Intestinal Carcinogenesis
(2022)
1127: Epithelial CGAS/STING Guides DNA Damage-driven Stem Cell Function and protect from Intestinal Carcinogenesis
Gastroenterology
May, 162:
7, Supplement; S-262
A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies
(2022)
A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies
Brain
Mar 28:awac119:
Ecology impacts the decrease of Spirochaetes and Prevotella in the fecal gut microbiota of urban humans
(2021)
Ecology impacts the decrease of Spirochaetes and Prevotella in the fecal gut microbiota of urban humans
BMC Microbiol
Oct 11;21(1):
276
Culturomics Approaches Expand the Diagnostic Accuracy for Sexually Transmitted Infections
(2021)
Culturomics Approaches Expand the Diagnostic Accuracy for Sexually Transmitted Infections
International Journal of Molecular Sciences
Oct. 6, 22(19):
10815
Circulating sDPP-4 is Increased in Obesity and Insulin Resistance but Is Not Related to Systemic Metabolic Inflammation
(2021)
Circulating sDPP-4 is Increased in Obesity and Insulin Resistance but Is Not Related to Systemic Metabolic Inflammation
J Clin Endocrinol Metab.
Jan 23; 106(2):
e592-e601
Precision Nutrition in Chronic Inflammation.
(2020)
Precision Nutrition in Chronic Inflammation.
Front. Immunol.
Nov; 11:
587895
Genomewide association study of psoriasis in Egyptian population
(2019)
Genomewide association study of psoriasis in Egyptian population
Exp. Dermatol.
May;28(5):
623-627
Increased phosphorylation of eNOS in nasal polyps of chronic rhinosinusitis patients can be diminished by 1,8-cineol.
(2018)
Increased phosphorylation of eNOS in nasal polyps of chronic rhinosinusitis patients can be diminished by 1,8-cineol.
Nitric Oxide.
Aug 1; 78:
89-94
Nuclear factor E2 related factor-2 differentially impacts on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells - a condition favouring metabolic symbiosis between colorectal cancer and stromal cells
(2018)
Nuclear factor E2 related factor-2 differentially impacts on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells - a condition favouring metabolic symbiosis between colorectal cancer and stromal cells
Oncogene
Jan 4;37(1):
39-51
Regulated proteolysis as an element of ER stress and autophagy: Implications for intestinal inflammation
(2017)
Regulated proteolysis as an element of ER stress and autophagy: Implications for intestinal inflammation
Biochim Biophys Acta Mol Cell Res.
1864(11 Pt B):
2183-2190
Detailed stratified GWAS analysis for severe COVID-19 in four European populations.
(2022)
Detailed stratified GWAS analysis for severe COVID-19 in four European populations.
Hum Mol Genet.
Jul 15:ddac158:
Distinct metabolite profile in pemphigus vulgaris
(2022)
Distinct metabolite profile in pemphigus vulgaris
J Invest Dermatol.
Jun 16; S0022-202X(22)01546-9:
Characterization of the skin microbiota in bullous pemphigoid patients and controls reveals novel microbial indicators of disease
(2022)
Characterization of the skin microbiota in bullous pemphigoid patients and controls reveals novel microbial indicators of disease
J Adv Res.
Apr. 4; S2090-1232(22)00081-9:
Linkage analysis identifies novel genetic modifiers of microbiome traits in families with inflammatory bowel disease
(2022)
Linkage analysis identifies novel genetic modifiers of microbiome traits in families with inflammatory bowel disease
Gut Microbes
Feb. 06 published online; 14(1), 2024415:
A novel unconventional T cell population enriched in Crohn’s disease
(2022)
A novel unconventional T cell population enriched in Crohn’s disease
Gut
March 09, online:
gutjnl-2021-325373
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
(2022)
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Cell Reports
March 08:
A day clinic for the interdisciplinary therapy of severe obesity.
(2021)
A day clinic for the interdisciplinary therapy of severe obesity.
Thieme-Diabetologie und Stoffwechsel
16(5):
393-400
Mast cell-deficient mice Mcpt5Cre/Dicerfl/fl redefine the role of mast cells in experimental bullous pemphigoid in skin health and disease.
(2021)
Mast cell-deficient mice Mcpt5Cre/Dicerfl/fl redefine the role of mast cells in experimental bullous pemphigoid in skin health and disease.
Skin Health Dis
Dec 21; e70:
Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis
(2021)
Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis
Cell Metabolism
Dec 7; 7:33(12):
2355-2366.e8
Mapping the human genetic architecture of COVID-19. COVID-19
(2021)
Mapping the human genetic architecture of COVID-19. COVID-19
Nature
online, 600:
472–477
65. Therapeutic Interleukin-6 Trans-signaling Inhibition by Olamkicept (sgp130Fc) in Patients With Active Inflammatory Bowel Disease
(2021)
65. Therapeutic Interleukin-6 Trans-signaling Inhibition by Olamkicept (sgp130Fc) in Patients With Active Inflammatory Bowel Disease
Gastroenterology
June; 160(7):
2354-2366.e11
Impact of First-Line Antimicrobials on Chlamydia trachomatis-Induced Changes in Host Metabolism and Cytokine Production
(2021)
Impact of First-Line Antimicrobials on Chlamydia trachomatis-Induced Changes in Host Metabolism and Cytokine Production
Front. Microbiol.
Aug 13;12::
676747
Role of ADAM10 and ADAM 17 in regulating CD 137 function.
(2021)
Role of ADAM10 and ADAM 17 in regulating CD 137 function.
Int.J.Mol.Sci.
March 08; 22(5):
2730
Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome
(2021)
Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome
Nature Genetics
Feb., 53(2):
147-155
Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associations.
(2021)
Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associations.
Hum. Mol. Genet.
Feb 8;ddab017:
NOD2 Influences Trajectories of Intestinal Microbiota Recovery After Antibiotic Perturbation.
(2020)
NOD2 Influences Trajectories of Intestinal Microbiota Recovery After Antibiotic Perturbation.
Cellular and Molecular Gastroenterology and Hepatology cmgh
10(2):
365-389
Stem Cells and Organoid Technology in Precision Medicine in Inflammation: Are We There Yet?
(2020)
Stem Cells and Organoid Technology in Precision Medicine in Inflammation: Are We There Yet?
Front. Immunol.
Dec. 21:
Autoantibody-negative insulin-dependent diabetes mellitus after SARS-CoV-2 infection: a case report
(2020)
Autoantibody-negative insulin-dependent diabetes mellitus after SARS-CoV-2 infection: a case report
Nature Metabolism
Oct:
55. Activating Transcription Factor 6 Mediates Inflammatory Signals in Intestinal Epithelial Cells Upon Endoplasmic Reticulum Stress
(2020)
55. Activating Transcription Factor 6 Mediates Inflammatory Signals in Intestinal Epithelial Cells Upon Endoplasmic Reticulum Stress
Gastroenterology
Oct; 159(4):
1357-1374.e10.
Nutritional Targeting of the Microbiome as Potential Therapy for Malnutrition and Chronic Inflammation
(2020)
Nutritional Targeting of the Microbiome as Potential Therapy for Malnutrition and Chronic Inflammation
Nutrients
Oct 3, 12(10):
3032
Unbiased characterization of peptide-HLA class II interactions based on large-scale peptide microarrays; assessment of the impact on HLA class II ligand and epitope prediction
(2020)
Unbiased characterization of peptide-HLA class II interactions based on large-scale peptide microarrays; assessment of the impact on HLA class II ligand and epitope prediction
Frontiers of Immunology
11:
1705
Inflammatory Bowel Disease and Epigenetics
(2019)
Inflammatory Bowel Disease and Epigenetics
Molecular Genetics of Inflammatory Bowel Disease, Springer, Cham.
Dec 20:
183-201
Gut mycobiome of primary sclerosing cholangitis patients is characterised by an increase of Trichocladium griseum and Candida species
(2019)
Gut mycobiome of primary sclerosing cholangitis patients is characterised by an increase of Trichocladium griseum and Candida species
Gut
Oct:
0:12
Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms
(2019)
Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms
Microbiome
7(1):
133
Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice
(2019)
Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice
Gastroenterology
156(1):
145-159.e19
Evolutionary Perspectives on the Human Gut Microbiome.
(2018)
Evolutionary Perspectives on the Human Gut Microbiome.
In: Haller D, editor. The Gut Microbiome in Health and Disease, Cham: Springer International Publishing
67-78
Grow With the Challenge – Microbial Effects on Epithelial Proliferation, Carcinogenesis, and Cancer Therapy
(2018)
35. Grow With the Challenge – Microbial Effects on Epithelial Proliferation, Carcinogenesis, and Cancer Therapy
Front. Microbiol.
Sept; 9:2020:
Microbiota-based analysis reveals specific bacterial traits and a novel strategy for the diagnosis of infectious infertility
(2018)
Microbiota-based analysis reveals specific bacterial traits and a novel strategy for the diagnosis of infectious infertility
PLOS Biology
13(1):e0191047:
156 Epidermal differentiation, inflammation, and serum levels of filaggrin and IgE in atopic dermatitis, classical prurigo nodularis and prurigo nodularis in AD.
(2017)
156 Epidermal differentiation, inflammation, and serum levels of filaggrin and IgE in atopic dermatitis, classical prurigo nodularis and prurigo nodularis in AD.
Journal of Investigative Dermatology
10, supplement 2:
S219
Extracellular sphingomyelinase activity impairs TNF-α-induced endothelial cell death via ADAM17 activation and TNF receptor 1 shedding
(2017)
Extracellular sphingomyelinase activity impairs TNF-α-induced endothelial cell death via ADAM17 activation and TNF receptor 1 shedding
Oncotarget
8(42):
72584–72596
Genotype imputation in case-only studies of gene-environment interaction: validity and power
(2021)
Genotype imputation in case-only studies of gene-environment interaction: validity and power
Hum Genet.
140(8):
1217-1228
Epithelial X-Box Binding Protein 1 Coordinates Tumor Protein p53-Driven DNA Damage Responses and Suppression of Intestinal Carcinogenesis
(2021 )
Epithelial X-Box Binding Protein 1 Coordinates Tumor Protein p53-Driven DNA Damage Responses and Suppression of Intestinal Carcinogenesis
Gastroenterology
S0016-5085(21)03606-4:
Online ahead of print.
Immunopeptidomics toolkit library (IPTK): a python-based modular toolbox for analyzing immunopeptidomics data
(2021)
Immunopeptidomics toolkit library (IPTK): a python-based modular toolbox for analyzing immunopeptidomics data
BMC Bioinformatics
Aug 17:
22(1)
The role of cGAS/STING in intestinal immunity
(2021)
The role of cGAS/STING in intestinal immunity
Eur J Immunol
Online ahead of print. :
Mutagenesis of the ADAM17-phosphatidylserine-binding motif leads to embryonic lethality in mice
(2019)
Mutagenesis of the ADAM17-phosphatidylserine-binding motif leads to embryonic lethality in mice
Life Sci Alliance
Aug 27;2(5) / Print 2019 Oct. :
e201900430
Case-only analysis of gene-gene interactions in inflammatory bowel disease
(2020)
Case-only analysis of gene-gene interactions in inflammatory bowel disease
Scand J Gastroenterol .
Aug;55(8):
897-906
Low avidity CD4+ T cell responses to SARS-CoV-2 in unexposed individuals and humans with severe COVID-19.
(2020)
Low avidity CD4+ T cell responses to SARS-CoV-2 in unexposed individuals and humans with severe COVID-19.
Immunity
Nov.:
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells and plasmablasts as hallmarks of severe COVID-19 trajectories.
(2020)
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells and plasmablasts as hallmarks of severe COVID-19 trajectories.
Immunity
Nov.:
Dissimilarity of Airway and Lung Tissue Microbiota in Smokers undergoing Surgery for Lung Cancer
(2020)
Dissimilarity of Airway and Lung Tissue Microbiota in Smokers undergoing Surgery for Lung Cancer
Microorganisms
2020 May 26:
8(6):794
Identification of disease-associated traits and clonotypes in the T-cell receptor repertoire of monozygotic twins affected by inflammatory bowel diseases.
(2020)
Identification of disease-associated traits and clonotypes in the T-cell receptor repertoire of monozygotic twins affected by inflammatory bowel diseases.
J Crohns Colitis
2020 Jul. 9:
14(6):778-790
Genomewide Association Study of Severe Covid-19 With Respiratory Failure
(2020)
Genomewide Association Study of Severe Covid-19 With Respiratory Failure
N Engl J Med .
2020 Jun 17:
Online ahead of print.
Amino acid encoding for deep learning applications
(2020)
Amino acid encoding for deep learning applications
BMC Bioinformatics
2020 Jun 9:
21(1):235
Construction and Benchmarking of a Multi-Ethnic Reference Panel for the Imputation of HLA Class I and II Alleles
(2019 )
Construction and Benchmarking of a Multi-Ethnic Reference Panel for the Imputation of HLA Class I and II Alleles
Hum Mol Genet .
2019 Jun 15:
28(12):2078-2092
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development
(2018)
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development
Genome Med.
13 / Apr 2018:
27
Secreted frizzled-related protein 5 serum levels in human periodontitis-A nested case-control study
(2019)
Secreted frizzled-related protein 5 serum levels in human periodontitis-A nested case-control study
J Clin Periodontol.j
May 2019; Epub 22 / Apr 2019:
522-528
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
(2019)
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
Nat Commun.
31 / Oct 2019:
4955
Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease
(2018)
Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease
Gut.
Jan 2019; Epub 5 / May 2018 :
25-39
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING
(2018)
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING
J Exp Med.
5 / Nov 2018; Epub 25 / Sep 2018:
2868-2886
The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding
(2015)
The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding
J Biol Chem.
20 / Mar 2015; Epub 20 / Jan 2015:
7416-25
Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation
(2014)
Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation
Free Radic Biol Med.
May 2014; Epub 12 / Mar 2014:
255-64
Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers
(2018)
Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers
BMC Cancer.
6 / Aug 2018:
796
Improved detection of gene-microbe interactions in the mouse skin microbiota using high-resolution QTL mapping of 16S rRNA transcripts
(2017)
Improved detection of gene-microbe interactions in the mouse skin microbiota using high-resolution QTL mapping of 16S rRNA transcripts
Microbiome.
6 / Jun 2017:
59
The retinoid-related orphan receptor alpha is essential for the end-stage effector phase of experimental epidermolysis bullosa acquisita
(2015)
The retinoid-related orphan receptor alpha is essential for the end-stage effector phase of experimental epidermolysis bullosa acquisita
J Pathol.
Sep 2015; Epub 15 / Jun 2015:
111-22
Radiosensitive Hematopoietic Cells Determine the Extent of Skin Inflammation in Experimental Epidermolysis Bullosa Acquisita
(2015)
Radiosensitive Hematopoietic Cells Determine the Extent of Skin Inflammation in Experimental Epidermolysis Bullosa Acquisita
J Immunol.
1 / Sep 2015; Epub 22 / Jul 2015:
1945-54
Autoantibodies to Multiple Epitopes on the Non-Collagenous-1 Domain of Type VII Collagen Induce Blisters
(2015)
Autoantibodies to Multiple Epitopes on the Non-Collagenous-1 Domain of Type VII Collagen Induce Blisters
J Invest Dermatol.
Jun 2015; Epub 17 / Feb 2015:
1565-1573
Recombinant soluble CD32 suppresses disease progression in experimental epidermolysis bullosa acquisita
(2014)
Recombinant soluble CD32 suppresses disease progression in experimental epidermolysis bullosa acquisita
J Invest Dermatol.
Mar 2015; Epub 20 / Oct 2014:
916-919
Elaborations on Corallopyronin A as a Novel Treatment Strategy Against Genital Chlamydial Infections
(2019)
Elaborations on Corallopyronin A as a Novel Treatment Strategy Against Genital Chlamydial Infections
Front Microbiol.
7 / May 2019:
943
Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
(2019)
Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
Nat Commun.
10 / Sep 2019:
4097
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING
(2018)
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING
Journal of experimental Medicine
2018 Sep 25:
Role of wnt5a in metabolic inflammation in humans
(2018)
Role of wnt5a in metabolic inflammation in humans
J Clin Endocrinol Metab.
2018 Aug 20. [Epub ahead of print]:
Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome
(2018)
Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome
Gastroenterology
Jul, Epub 2018 Apr 5:
168-179
Faecal microbiota composition associates with abdominal pain in the general population
(2018)
Faecal microbiota composition associates with abdominal pain in the general population
Gut
Apr, Epub 2017 Aug 1:
778-779
Effective inhibition of rifampin-resistant Chlamydia trachomatis by the novel DNA-dependent RNA-polymerase inhibitor Corallopyronin A
(2018)
Effective inhibition of rifampin-resistant Chlamydia trachomatis by the novel DNA-dependent RNA-polymerase inhibitor Corallopyronin A
International Journal of Antimicrobial Agents, Available online 6 August 2018
Selection of validated hypervariable regions is crucial in 16S-based microbiota studies of the female genital tract
(2018)
Selection of validated hypervariable regions is crucial in 16S-based microbiota studies of the female genital tract
Nature, Scientific Reports. volume 8, article number: 9678 (2018)
On a Western diet, APOE ε4 is associated with low innate immune sensing, but not APOE ε3
(2018)
On a Western diet, APOE ε4 is associated with low innate immune sensing, but not APOE ε3
J Allergy Clin Immunol. 2018 Jun 18. [Epub ahead of print]
Microbiota changes impact on sexually transmitted infections and the development of pelvic inflammatory disease
(2018)
Microbiota changes impact on sexually transmitted infections and the development of pelvic inflammatory disease
Microbes and Infection
doi: 10.1016/j.micinf.2018.02.003:
in press, accepted manuscript
Microbiota-based analysis reveals specific bacterial traits and a novel strategy for the diagnosis of infectious infertility
(2018)
Microbiota-based analysis reveals specific bacterial traits and a novel strategy for the diagnosis of infectious infertility
PLOS Biology
Jan. 9:
https://doi.org/10.1371/journal.pone.0191047
Gene Expression Analysis Reveals Novel Shared Gene Signatures and Candidate Molecular Mechanisms between Pemphigus and Systemic Lupus Erythematosus in CD4+ T Cells
(2018)
Gene Expression Analysis Reveals Novel Shared Gene Signatures and Candidate Molecular Mechanisms between Pemphigus and Systemic Lupus Erythematosus in CD4+ T Cells
Front. Immunol.
17. January:
ePub 17. January 2018
Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome
(2016 )
Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome
Gut
Nov 21, epub ahead of print:
A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency
(2017)
A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency
Gut
April, epub 2016 Jul 29:
756-758
Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans
(2017)
Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans
Diabetes Care
epub ahead of print :
Identification and characterization of two functional variants in the human longevity gene FOXO3
(2017)
Identification and characterization of two functional variants in the human longevity gene FOXO3
nature
Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice.
(2017)
Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice.
Gastro
153(2):
550-565
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
(2017)
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Nat Med.
23(7):
829-838
Impact of micro-environmental changes on respiratory tract infections with intracellular bacteria.
(2016)
Impact of micro-environmental changes on respiratory tract infections with intracellular bacteria.
FEBS Lett.
Nov/590(21):
3887-3904
Overview of methodologies for T-cell receptor repertoire analysis.
(2017)
Overview of methodologies for T-cell receptor repertoire analysis.
BMC Biotechnology
Jul 10;17(1):61:
Hypothalamic Inflammation in Human Obesity is Mediated by Environmental and Genetic Factors.
(2017)
Hypothalamic Inflammation in Human Obesity is Mediated by Environmental and Genetic Factors.
Diabetes
epub ahead of print:
Quantitative Trait Locus Analysis Implicates CD4+/CD44high Memory T Cells in the Pathogenesis of Murine Autoimmune Pancreatitis
(2015)
Quantitative Trait Locus Analysis Implicates CD4+/CD44high Memory T Cells in the Pathogenesis of Murine Autoimmune Pancreatitis
PLoS One
Sept 1:
10(9)
Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.
(2017)
Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.
J. Exp. Med.
Jan 12:
epub ahead of print
TRPM8 polymorphisms associated with increased risk of IBS-C and IBS-M
(2016)
TRPM8 polymorphisms associated with increased risk of IBS-C and IBS-M
Gut
14 Dec.:
epub ahead of print
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.
(2016)
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.
Nat Genet.
Nov;48(11):
1396-1406
Classic IL-6R signalling is dispensable for intestinal epithelial proliferation and repair
(2016)
Classic IL-6R signalling is dispensable for intestinal epithelial proliferation and repair
Oncogenesis
Nov 21:
5(11):e270.
bcRep: R Package for Comprehensive Analysis of B Cell Receptor Repertoire Data
(2016)
bcRep: R Package for Comprehensive Analysis of B Cell Receptor Repertoire Data
PLoS One
Aug 23;11(8):
:e0161569
Paternal chronic colitis causes epigenetic inheritance of susceptibility to colitis.
(2016)
Paternal chronic colitis causes epigenetic inheritance of susceptibility to colitis.
Sci Rep.
6 / Aug 19:
31640
APOE gentotype and stress response – a mini review
(2016)
APOE gentotype and stress response – a mini review
Lipids in Health and Disease
Jul 25:
15:121
Epithelial IL-23R signaling licenses protective IL-22 responses in intestinal inflammation
(2016)
Epithelial IL-23R signaling licenses protective IL-22 responses in intestinal inflammation
Cell Reports
accepted, more information soon:
Chlamydia trachomatis as the cause of infectious infertility: acute, repetitive or persistent long-term infection?
(2016)
Chlamydia trachomatis as the cause of infectious infertility: acute, repetitive or persistent long-term infection?
Current Topics in Microbiology and Immunology
02 July:
Phosphatidylserine exposure is required for ADAM17 sheddase function
(2016)
Phosphatidylserine exposure is required for ADAM17 sheddase function
Nature Communications
May 10;7:
article no 11523
Influence of the APOE genotype on hepatic stress response: Studies in APOE targeted replacement mice and human liver cells
(2016)
Influence of the APOE genotype on hepatic stress response: Studies in APOE targeted replacement mice and human liver cells
Free Radical Biology and Medicine
April 26. pii: S0891-5849(16)30049-1. doi: 10.1016/j.freeradbiomed.2016.04.031. [Epub ahead of print]:
Stool frequency is associated with gut microbiota composition
(2016)
Stool frequency is associated with gut microbiota composition
Gut
Apr 28, epub ahead of print:
Dissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease.
(2016)
Dissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease.
BMC Genomics
Feb 16;17(1):
112
Characteristic changes in microbial community composition and expression of innate immune genes in acute appendicitis.
(2013)
Characteristic changes in microbial community composition and expression of innate immune genes in acute appendicitis.
Innate Immun.
Jan 21(1):
30-41
Host immune responses after hypoxic reactivation of IFN-γ induced persistent Chlamydia trachomatis infection.
(2014)
Host immune responses after hypoxic reactivation of IFN-γ induced persistent Chlamydia trachomatis infection.
Front Cell Inf Microb
Apr 16:
4:34
Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration
(2014)
Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration
Gut
Dec;63(12):
1921-31
Paneth cells as a site of origin for intestinal inflammation
(2013)
Paneth cells as a site of origin for intestinal inflammation
Nature
Nov 14;503(7475):
272-6
Allowing for population stratification in case-only studies of gene-environment interaction, using genomic control.
(2015)
Allowing for population stratification in case-only studies of gene-environment interaction, using genomic control.
Hum Genet.
Oct;134(10)::
1117-25
Extracellular Juxtamembrane Segment of ADAM17 Interacts with Membranes and Is Essential for Its Shedding Activity.
(2015)
Extracellular Juxtamembrane Segment of ADAM17 Interacts with Membranes and Is Essential for Its Shedding Activity.
Biochemistry
Sept 29, 54(38):
5791-801
Genomics and drug profiling of fatal TCF3-HLF−positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options
(2015)
Genomics and drug profiling of fatal TCF3-HLF−positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options
Nature Genetics
online July 27, doi:10.1038/ng.3362:
47(9):1020-9
The anti-atherogenic effect of fish oil in male mice is associated with a diminished release of endothelial ADAM17 and ADAM10 substrates
(2015)
The anti-atherogenic effect of fish oil in male mice is associated with a diminished release of endothelial ADAM17 and ADAM10 substrates
J Nutr.
Jun; 145(6)::
1218-26
Apolipoprotein E (APOE) genotype regulates body weight and fatty acid utilization-Studies in gene-targeted replacement mice.
(2015)
Apolipoprotein E (APOE) genotype regulates body weight and fatty acid utilization-Studies in gene-targeted replacement mice.
Mol Nutr Food Res.
Feb;59 (2):
334-43
ptRNApred: computational identification and classification of post-transcriptional RNA
(2014)
ptRNApred: computational identification and classification of post-transcriptional RNA
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