Publications

Dissimilarity of Airway and Lung Tissue Microbiota in Smokers undergoing Surgery for Lung Cancer
Lena Reinhold, Andreas Möllering, Sönke Wallis, Emanuel Palade, Kathrin Schäfer, Daniel Drömann, Jan Rupp, Simon Graspeuntner, Klaus Dalhoff
(2020)
Dissimilarity of Airway and Lung Tissue Microbiota in Smokers undergoing Surgery for Lung Cancer
Microorganisms
2020 May 26:
8(6):794
Pubmed - PMID
Identification of disease-associated traits and clonotypes in the T-cell receptor repertoire of monozygotic twins affected by inflammatory bowel diseases.
Rosati E, Pogorelyy MV, Dowds CM, Moller FT, Sorensen SB, Lebedev YB, Frey N, Schreiber S, Spehlmann ME, Andersen V, Franke A.
(2020)
Identification of disease-associated traits and clonotypes in the T-cell receptor repertoire of monozygotic twins affected by inflammatory bowel diseases.
J Crohns Colitis
2020 Jul. 9:
14(6):778-790
Pubmed - PMID 31711184
Genomewide Association Study of Severe Covid-19 With Respiratory Failure
D Ellinghaus, F Degenhardt, L Bujanda, M Buti, A Albillos, P Invernizzi, J Fernández, D Prati, G Baselli, R Asselta, M M Grimsrud, C Milani, F Aziz, J Kässens, S May, M Wendorff, L Wienbrandt, F Uellendahl-Werth, T Zheng, X Yi, R de Pablo, A G Chercoles, A Palom, A-E Garcia-Fernandez, F Rodriguez-Frias, A Zanella, A Bandera, A Protti, A Aghemo, A Lleo, A Biondi, A Caballero-Garralda, A Gori, A Tanck, A Carreras Nolla, A Latiano, A Ludovica Fracanzani, A Peschuck, A Julià, A Pesenti, A Voza, D Jiménez, B Mateos, B Nafria Jimenez, C Quereda, C Paccapelo, C Gassner, C Angelini, C Cea, A Solier, D Pestaña, E Muñiz-Diaz, E Sandoval, E M Paraboschi, E Navas, F García Sánchez, F Ceriotti, F Martinelli-Boneschi, F Peyvandi, F Blasi, L Téllez, A Blanco-Grau, G Hemmrich-Stanisak, G Grasselli, G Costantino, G Cardamone, G Foti, S Aneli, H Kurihara, H ElAbd, I My, I Galván-Femenia, J Martín, J Erdmann, J Ferrusquía-Acosta, K Garcia-Etxebarria, L Izquierdo-Sanchez, L R Bettini, L Sumoy, L Terranova, L Moreira, L Santoro, L Scudeller, F Mesonero, L Roade, M C Rühlemann, M Schaefer, M Carrabba, M Riveiro-Barciela, M E Figuera Basso, M G Valsecchi, M Hernandez-Tejero, M Acosta-Herrera, M D'Angiò, M Baldini, M Cazzaniga, M Schulzky, M Cecconi, M Wittig, M Ciccarelli, M Rodríguez-Gandía, M Bocciolone, M Miozzo, N Montano, N Braun, N Sacchi, N Martínez, O Özer, O Palmieri, P Faverio, P Preatoni, P Bonfanti, P Omodei, P Tentorio, P Castro, P M Rodrigues, A Blandino Ortiz, R de Cid, R Ferrer, R Gualtierotti, R Nieto, S Goerg, S Badalamenti, S Marsal, G Matullo, S Pelusi, S Juzenas, S Aliberti, V Monzani, V Moreno, T Wesse, T L Lenz, T Pumarola, V Rimoldi, S Bosari, W Albrecht, W Peter, M Romero-Gómez, M D'Amato, S Duga, J M Banales, J R Hov, T Folseraas, L Valenti, A Franke, T H Karlsen, Severe Covid-19 GWAS Group
(2020)
Genomewide Association Study of Severe Covid-19 With Respiratory Failure
N Engl J Med .
2020 Jun 17:
Online ahead of print.
DOI: 10.1056/NEJMoa2020283
Amino acid encoding for deep learning applications
Hesham ElAbd, Yana Bromberg, Adrienne Hoarfrost, Tobias Lenz, Andre Franke, Mareike Wendorff
(2020)
Amino acid encoding for deep learning applications
BMC Bioinformatics
2020 Jun 9:
21(1):235
Pubmed - PMID
Construction and Benchmarking of a Multi-Ethnic Reference Panel for the Imputation of HLA Class I and II Alleles
Frauke Degenhardt, Mareike Wendorff, Michael Wittig, Eva Ellinghaus, Lisa W Datta, John Schembri, Siew C Ng, Elisa Rosati, Matthias Hübenthal, David Ellinghaus, Eun Suk Jung, Wolfgang Lieb, Shifteh Abedian, Reza Malekzadeh, Jae Hee Cheon, Pierre Ellul, Ajit Sood, Vandana Midha, B K Thelma, Sunny H Wong, Stefan Schreiber, Keiko Yamazaki, Michiaki Kubo, Gabrielle Boucher, John D Rioux, Tobias L Lenz, Steven R Brant, Andre Franke
(2019 )
Construction and Benchmarking of a Multi-Ethnic Reference Panel for the Imputation of HLA Class I and II Alleles
Hum Mol Genet .
2019 Jun 15:
28(12):2078-2092
Pubmed - PMID
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development
Pan WH, Sommer F, Falk-Paulsen M, Ulas T, Best P, Fazio A, Kachroo P, Luzius A, Jentzsch M, Rehman A, Müller F, Lengauer T, Walter J, Künzel S, Baines JF, Schreiber S, Franke A, Schultze JL, Bäckhed F, Rosenstiel P
(2018)
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development
Genome Med.
13 / Apr 2018:
27
Pubmed - PMID
Secreted frizzled-related protein 5 serum levels in human periodontitis-A nested case-control study
Schulz J, Knappe C, Graetz C, Mewes L, Türk K1, Black AK, Lieb W, Schäfer AS, Fawzy El-Sayed KM, Dörfer CE, Schreiber S, Laudes M, Schulte DM
(2019)
Secreted frizzled-related protein 5 serum levels in human periodontitis-A nested case-control study
J Clin Periodontol.j
May 2019; Epub 22 / Apr 2019:
522-528
Pubmed - PMID
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
López-Isac E, Acosta-Herrera M, Kerick M, Assassi S, Satpathy AT, Granja J, Mumbach MR, Beretta L, Simeón CP, Carreira P, Ortego-Centeno N, Castellvi I, Bossini-Castillo L, Carmona FD, Orozco G, Hunzelmann N, Distler JHW, Franke A, Lunardi C, Moroncini G, Gabrielli A, de Vries-Bouwstra J, Wijmenga C, Koeleman BPC, Nordin A, Padyukov L, Hoffmann-Vold AM, Lie B; European Scleroderma Group (...Riemekasten G et al), Proudman S, Stevens W, Nikpour M; Australian Scleroderma Interest Group (ASIG), Vyse T, Herrick AL, Worthington J, Denton CP, Allanore Y, Brown MA, Radstake TRDJ, Fonseca C, Chang HY, Mayes MD, Martin J
(2019)
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
Nat Commun.
31 / Oct 2019:
4955
Pubmed - PMID
Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease
Zeissig S, Rosati E, Dowds CM, Aden K, Bethge J, Schulte B, Pan WH, Mishra N, Zuhayra M, Marx M, Paulsen M, Strigli A, Conrad C, Schuldt D, Sinha A, Ebsen H, Kornell SC, Nikolaus S, Arlt A, Kabelitz D, Ellrichmann M, Lützen U, Rosenstiel PC, Franke A, Schreiber S
(2018)
Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease
Gut.
Jan 2019; Epub 5 / May 2018 :
25-39
Pubmed - PMID
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING
Aden K1,2, Tran F1,2, Ito G1,3, Sheibani-Tezerji R1, Lipinski S1, Kuiper JW1, Tschurtschenthaler M4,5, Saveljeva S5, Bhattacharyya J5, Häsler R1, Bartsch K6, Luzius A1, Jentzsch M1, Falk-Paulsen M1, Stengel ST1, Welz L1, Schwarzer R7, Rabe B6, Barchet W8, Krautwald S9, Hartmann G8, Pasparakis M7, Blumberg RS, Schreiber S, Kaser A, Rosenstiel P
(2018)
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING
J Exp Med.
5 / Nov 2018; Epub 25 / Sep 2018:
2868-2886
Pubmed - PMID
The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding
Maretzky T, Evers A, Le Gall S, Alabi RO, Speck N, Reiss K, Blobel CP
(2015)
The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding
J Biol Chem.
20 / Mar 2015; Epub 20 / Jan 2015:
7416-25
Pubmed - PMID
Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation
Piegholdt S, Pallauf K, Esatbeyoglu T, Speck N, Reiss K, Ruddigkeit L, Stocker A, Huebbe P, Rimbach G
(2014)
Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation
Free Radic Biol Med.
May 2014; Epub 12 / Mar 2014:
255-64
Pubmed - PMID
Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers
Kordowski F, Kolarova J, Schafmayer C, Buch S, Goldmann T, Marwitz S, Kugler C, Scheufele S, Gassling V, Németh CG, Brosch M, Hampe J, Lucius R, Röder C, Kalthoff H, Siebert R, Ammerpohl O, Reiss K
(2018)
Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers
BMC Cancer.
6 / Aug 2018:
796
Pubmed - PMID
Improved detection of gene-microbe interactions in the mouse skin microbiota using high-resolution QTL mapping of 16S rRNA transcripts
Belheouane M, Gupta Y, Künzel S, Ibrahim S, Baines JF
(2017)
Improved detection of gene-microbe interactions in the mouse skin microbiota using high-resolution QTL mapping of 16S rRNA transcripts
Microbiome.
6 / Jun 2017:
59
Pubmed - PMID
The retinoid-related orphan receptor alpha is essential for the end-stage effector phase of experimental epidermolysis bullosa acquisita
Sadeghi H, Gupta Y, Möller S, Samavedam UK, Behnen M, Kasprick A, Bieber K, Müller S, Kalies K, de Castro Marques A, Recke A, Schmidt E, Zillikens D, Laskay T, Mariani J, Ibrahim SM, Ludwig RJ
(2015)
The retinoid-related orphan receptor alpha is essential for the end-stage effector phase of experimental epidermolysis bullosa acquisita
J Pathol.
Sep 2015; Epub 15 / Jun 2015:
111-22
Pubmed - PMID
Radiosensitive Hematopoietic Cells Determine the Extent of Skin Inflammation in Experimental Epidermolysis Bullosa Acquisita
Iwata H, Witte M, Samavedam UK, Gupta Y, Shimizu A, Ishiko A, Schröder T, Seeger K, Dahlke M, Rades D, Zillikens D, Ludwig RJ
(2015)
Radiosensitive Hematopoietic Cells Determine the Extent of Skin Inflammation in Experimental Epidermolysis Bullosa Acquisita
J Immunol.
1 / Sep 2015; Epub 22 / Jul 2015:
1945-54
Pubmed - PMID
Autoantibodies to Multiple Epitopes on the Non-Collagenous-1 Domain of Type VII Collagen Induce Blisters
Vorobyev A, Ujiie H, Recke A, Buijsrogge JJA, Jonkman MF, Pas HH, Iwata H, Hashimoto T, Kim SC, Hoon Kim J, Groves R, Samavedam U, Gupta Y, Schmidt E, Zillikens D, Shimizu H, Ludwig RJ
(2015)
Autoantibodies to Multiple Epitopes on the Non-Collagenous-1 Domain of Type VII Collagen Induce Blisters
J Invest Dermatol.
Jun 2015; Epub 17 / Feb 2015:
1565-1573
Pubmed - PMID
Recombinant soluble CD32 suppresses disease progression in experimental epidermolysis bullosa acquisita
Iwata H, Pipi E, Möckel N, Sondermann P, Vorobyev A, van Beek N, Zillikens D, Ludwig RJ
(2014)
Recombinant soluble CD32 suppresses disease progression in experimental epidermolysis bullosa acquisita
J Invest Dermatol.
Mar 2015; Epub 20 / Oct 2014:
916-919
Pubmed - PMID
Elaborations on Corallopyronin A as a Novel Treatment Strategy Against Genital Chlamydial Infections
Loeper N, Graspeuntner S, Ledig S, Kaufhold I, Hoellen F, Schiefer A, Henrichfreise B, Pfarr K, Hoerauf A, Shima K, Rupp J
(2019)
Elaborations on Corallopyronin A as a Novel Treatment Strategy Against Genital Chlamydial Infections
Front Microbiol.
7 / May 2019:
943
Pubmed - PMID
Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
Vorobyev A, Gupta Y, Sezin T, Koga H, Bartsch Y C, Belheouane M, Künzel S, Sina C, Schilf P, Körber-Ahrens H, Beltsiou F, Ernst A L, Khil’chenko S, Al-Aasam H, Manz R A, Diehl S, Steinhaus M, Jascholt J, Kouki P, Boehncke W-H, Mayadas T N, Zillikens D, Sadik C D, Nishi H, Ehlers M, Möller S, Bieber K, Baines J F, Ibrahim S M & Ludwig R J
(2019)
Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
Nat Commun.
10 / Sep 2019:
4097
Pubmed - PMID
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING
K. Aden, F. Tran, G. Ito, R. Sheibani-Tezerji, S. Lipinski, J. W. Kuiper, M. Tschurtschenthaler, S. Saveljeva, P. Bhattacharyya, R. Häsler, K. Bartsch, A. Luzius, M. Jentzsch, M. Falk-Paulsen, S. T. Stengel, L. Welz, R. Schwarzer, B. Rabe, W. Barchet, S. Krautwald, G. Hartmann, M. Pasparakis, R.S. Blumberg, S. Schreiber, A. Kaser, P. Rosenstiel
(2018)
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING
Journal of experimental Medicine
2018 Sep 25:
Pubmed - PMID
Role of wnt5a in metabolic inflammation in humans
Relling I, Akcay G, Fangmann D, Knappe C, Schulte DM, Hartmann K, Müller N, Türk K, Dempfle A, Franke A, Schreiber S, Laudes M
(2018)
Role of wnt5a in metabolic inflammation in humans
J Clin Endocrinol Metab.
2018 Aug 20. [Epub ahead of print]:
Pubmed - PMID
Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome
Bonfiglio F, Zheng T, Garcia-Etxebarria K, Hadizadeh F, Bujanda L, Bresso F, Agreus L, Andreasson A, Dlugosz A, Lindberg G, Schmidt PT, Karling P, Ohlsson B, Simren M, Walter S, Nardone G, Cuomo R, Usai-Satta P, Galeazzi F, Neri M, Portincasa P, Bellini M, Barbara G, Latiano A, Hübenthal M, Thijs V, Netea MG, Jonkers D, Chang L, Mayer EA, Wouters MM, Boeckxstaens G, Camilleri M, Franke A, Zhernakova A, D'Amato M
(2018)
Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome
Gastroenterology
Jul, Epub 2018 Apr 5:
168-179
Pubmed - PMID
Faecal microbiota composition associates with abdominal pain in the general population
Hadizadeh F, Bonfiglio F, Belheouane M, Vallier M, Sauer S, Bang C, Bujanda L, Andreasson A, Agreus L, Engstrand L, Talley NJ, Rafter J, Baines JF, Walter S, Franke A, D'Amato M
(2018)
Faecal microbiota composition associates with abdominal pain in the general population
Gut
Apr, Epub 2017 Aug 1:
778-779
Pubmed - PMID
Effective inhibition of rifampin-resistant Chlamydia trachomatis by the novel DNA-dependent RNA-polymerase inhibitor Corallopyronin A
Kensuke Shimaa, Svea Ledig, Nathalie Loeper, Andrea Schieferd, Kenneth Pfarre, Achim Hoerauf, Simon Graspeuntner, Jan Rupp
(2018)
Effective inhibition of rifampin-resistant Chlamydia trachomatis by the novel DNA-dependent RNA-polymerase inhibitor Corallopyronin A
International Journal of Antimicrobial Agents, Available online 6 August 2018
Pubmed - PMID
Selection of validated hypervariable regions is crucial in 16S-based microbiota studies of the female genital tract
Simon Graspeuntner, Nathalie Loeper, Sven Künzel, John F. Baines & Jan Rupp
(2018)
Selection of validated hypervariable regions is crucial in 16S-based microbiota studies of the female genital tract
Nature, Scientific Reports. volume 8, article number: 9678 (2018)
Pubmed - PMID
On a Western diet, APOE ε4 is associated with low innate immune sensing, but not APOE ε3
Janina Dose, Anke Schloesser, Guillermo G. Torres, Geetha Venkatesh, Robert Häsler, Friederike Flachsbart, Wolfgang Lieb, Almut Nebel, Gerald Rimbach, Patricia Huebbe
(2018)
On a Western diet, APOE ε4 is associated with low innate immune sensing, but not APOE ε3
J Allergy Clin Immunol. 2018 Jun 18. [Epub ahead of print]
Pubmed - PMID 29928926
Microbiota changes impact on sexually transmitted infections and the development of pelvic inflammatory disease
Nathalie Loeper, Simon Graspeuntner, Jan Rupp
(2018)
Microbiota changes impact on sexually transmitted infections and the development of pelvic inflammatory disease
Microbes and Infection
doi: 10.1016/j.micinf.2018.02.003:
in press, accepted manuscript
Pubmed - PMID
Microbiota-based analysis reveals specific bacterial traits and a novel strategy for the diagnosis of infectious infertility
Simon Graspeuntner, Michael K. Bohlmann, Kathrin Gillmann, Runa Speer, Sven Kuenzel, Heike Mark, Friederike Hoellen, Reinhard Lettau, Georg Griesinger, Inke R. König, John F. Baines, Jan Rupp
(2018)
Microbiota-based analysis reveals specific bacterial traits and a novel strategy for the diagnosis of infectious infertility
PLOS Biology
Jan. 9:
https://doi.org/10.1371/journal.pone.0191047
Pubmed - PMID
Gene Expression Analysis Reveals Novel Shared Gene Signatures and Candidate Molecular Mechanisms between Pemphigus and Systemic Lupus Erythematosus in CD4+ T Cells
Sezin T, Vorobyev A, Sadik C, Zillikens D, Gupta Y, Ludwig R
(2018)
Gene Expression Analysis Reveals Novel Shared Gene Signatures and Candidate Molecular Mechanisms between Pemphigus and Systemic Lupus Erythematosus in CD4+ T Cells
Front. Immunol.
17. January:
ePub 17. January 2018
Pubmed - PMID
Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome
Henström M, Diekmann L, Bonfiglio F, Hadizadeh F, Kuech EM, von Köckritz-Blickwede M, Thingholm LB, Zheng T, Assadi G, Dierks C, Heine M, Philipp U, Distl O, Money ME, Belheouane M, Heinsen FA, Rafter J, Nardone G, Cuomo R, Usai-Satta P, Galeazzi F, Neri M, Walter S, Simrén M, Karling P, Ohlsson B, Schmidt PT, Lindberg G, Dlugosz A, Agreus L, Andreasson A, Mayer E, Baines JF, Engstrand L, Portincasa P, Bellini M, Stanghellini V, Barbara G, Chang L, Camilleri M, Franke A, Naim HY, D'Amato M
(2016 )
Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome
Gut
Nov 21, epub ahead of print:
Pubmed - PMID
A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency
Jankipersadsing SA, Hadizadeh F, Bonder MJ, Tigchelaar EF, Deelen P, Fu J, Andreasson A, Agreus L, Walter S, Wijmenga C, Hysi P, D'Amato M, Zhernakova A.
(2017)
A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency
Gut
April, epub 2016 Jul 29:
756-758
Pubmed - PMID
Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans
Fangmann D, Theismann EM, Türk K, Schulte DM, Relling I, Hartmann K, Keppler JK, Knipp JR, Rehman A, Heinsen FA, Franke A, Lenk L, Freitag-Wolf S, Appel E, Gorb S, Brenner C, Seegert D, Waetzig GH, Rosenstiel P, Schreiber S, Schwarz K, Laudes M.
(2017)
Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans
Diabetes Care
epub ahead of print :
Pubmed - PMID 29212824
Identification and characterization of two functional variants in the human longevity gene FOXO3
Flachsbart F, Dose J, Gentschew L, Geismann C, Caliebe A, Knecht C, Nygaard M, Badarinarayan N, ElSharawy A, May S, Luzius A, Torres GG, Jentzsch M, Forster M, Häesler R, Pallauf K, Lieb W, Derbois C, Galan P, Drichel D, Arlt A, Andreas Till A, Krause-Kyora B, Rimbach G, Blanché H, Deleuze J-F, Christiansen L, Christensen K, Nothnagel M, Rosenstiel P, Schreiber S, Franke A, Sebens S, Nebel A.
(2017)
Identification and characterization of two functional variants in the human longevity gene FOXO3
nature
Pubmed - PMID
Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice.
Pankaj Yadav,* David Ellinghaus,* Gaëlle Rémy, Sandra Freitag-Wolf, Anabelle Cesaro, Frauke Degenhardt, Gabrielle Boucher, Myriam Delacre, The International IBD Genetics Consortium (IIBDGC), Laurent Peyrin-Biroulet, Muriel Pichavant, John D Rioux, Philippe Gosset, Andre Franke, L. Philip Schumm, Michael Krawczak, Mathias Chamaillard, Astrid Dempfle, and Vibeke Andersen
(2017)
Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice.
Gastro
153(2):
550-565
Pubmed - PMID 28506689
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Giles DA, Moreno-Fernandez ME, Stankiewicz TE Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S.
(2017)
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Nat Med.
23(7):
829-838
Pubmed - PMID 28604704
Impact of micro-environmental changes on respiratory tract infections with intracellular bacteria.
Shima K, Coopmeiners J, Graspeuntner S, Dalhoff K, Rupp J.
(2016)
Impact of micro-environmental changes on respiratory tract infections with intracellular bacteria.
FEBS Lett.
Nov/590(21):
3887-3904
Pubmed - PMID 27509029
Overview of methodologies for T-cell receptor repertoire analysis.
Rosati, E., Dowds, C.M., Liaskou, E., Henriksen, E.K.K., Karlsen, T.H., Franke, A.
(2017)
Overview of methodologies for T-cell receptor repertoire analysis.
BMC Biotechnology
Jul 10;17(1):61:
Pubmed - PMID 28693542
Hypothalamic Inflammation in Human Obesity is Mediated by Environmental and Genetic Factors.
Kreutzer C, Peters S, Schulte DM, Fangmann D, Türk K, Wolff S, van Eimeren T, Ahrens M, Beckmann J, Schafmayer C, Becker T, Kerby T, Rohr A, Riedel C, Heinsen FA, Degenhardt F, Franke A, Rosenstiel P, Zubek N, Henning C, Freitag-Wolf S, Dempfle A, Psilopanagioti A, Petrou-Papadaki H, Lenk L, Jansen O, Schreiber S, Laudes M
(2017)
Hypothalamic Inflammation in Human Obesity is Mediated by Environmental and Genetic Factors.
Diabetes
epub ahead of print:
Pubmed - PMID 28576837
Quantitative Trait Locus Analysis Implicates CD4+/CD44high Memory T Cells in the Pathogenesis of Murine Autoimmune Pancreatitis
Bischof J., Müller S., Borufka L., Asghari F., Möller S., Holzhüter SA., Nizze H., Ibrahim SM., Jaster R.
(2015)
Quantitative Trait Locus Analysis Implicates CD4+/CD44high Memory T Cells in the Pathogenesis of Murine Autoimmune Pancreatitis
PLoS One
Sept 1:
10(9)
Pubmed - PMID 26325540
Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.
Tschurtschenthaler M, Adolph TE, Ashcroft JW, Niederreiter L, Bharti R, Saveljeva S, Bhattacharyya J, Flak MB3, Shih DQ, Fuhler GM, Parkes M, Kohno K, Iwawaki T, Janneke van der Woude C, Harding HP, Smith AM, Peppelenbosch MP, Targan SR, Ron D, Rosenstiel P, Blumberg RS, Kaser A.
(2017)
Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.
J. Exp. Med.
Jan 12:
epub ahead of print
Pubmed - PMID 28082357
TRPM8 polymorphisms associated with increased risk of IBS-C and IBS-M
Henström M, Hadizadeh F, Beyder A, Bonfiglio F, Zheng T, Assadi G, Rafter J, Bujanda L, Agreus L, Andreasson A, Dlugosz A, Lindberg G, Schmidt PT7, Karling P, Ohlsson B, Talley NJ, Simren M, Walter S, Wouters M, Farrugia G, D'Amato M.
(2016)
TRPM8 polymorphisms associated with increased risk of IBS-C and IBS-M
Gut
14 Dec.:
epub ahead of print
Pubmed - PMID 27974553
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.
Wang J, Thingholm LB, Skiecevičienė J, Rausch P, Kummen M, Hov JR, Degenhardt F, Heinsen FA, Rühlemann MC, Szymczak S, Holm K, Esko T, Sun J, Pricop-Jeckstadt M, Al-Dury S, Bohov P, Bethune J, Sommer F, Ellinghaus D, Berge RK, Hübenthal M, Koch M, Schwarz K, Rimbach G, Hübbe P, Pan WH, Sheibani-Tezerji R, Häsler R, Rosenstiel P, D'Amato M, Cloppenborg-Schmidt K, Künzel S, Laudes M, Marschall HU, Lieb W, Nöthlings U, Karlsen TH, Baines JF, Franke A.
(2016)
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.
Nat Genet.
Nov;48(11):
1396-1406
Pubmed - PMID 27723756
Classic IL-6R signalling is dispensable for intestinal epithelial proliferation and repair
Aden K, Breuer A, Geese H, Tran F, Sommer J, Waetzig G, Reinheimer T, Schreiber S, Rose-John S, Scheller J, Rosenstiel P, Rehman A
(2016)
Classic IL-6R signalling is dispensable for intestinal epithelial proliferation and repair
Oncogenesis
Nov 21:
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