Publications

Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
Artem Vorobyev, Yask Gupta, Tanya Sezin, Hiroshi Koga, Yannic C Bartsch, Meriem Belheouane, Sven Künzel, Christian Sina, Paul Schilf, Heiko Körber-Ahrens, Foteini Beltsiou, Anna Lara Ernst, Stanislav Khil'chenko, Hassanin Al-Aasam, Rudolf A Manz, Sandra Diehl, Moritz Steinhaus, Joanna Jascholt, Phillip Kouki, Wolf-Henning Boehncke, Tanya N Mayadas, Detlef Zillikens, Christian D Sadik, Hiroshi Nishi, Marc Ehlers, Steffen Möller, Katja Bieber, John F Baines, Saleh M Ibrahim, Ralf J Ludwig
(2019 Sep 10)
Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
Nat Commun.
10:
4097
Biodiversity of mycobial communities in health and onychomycosis
Michael Olbrich,# Anna Lara Ernst,# Foteini Beltsiou, Katja Bieber, Sascha Ständer, Melanie Harder, Waltraud Anemüller, Birgit Köhler, Detlef Zillikens, Hauke Busch, Axel Künstner and Ralf J. Ludwig
(2022, May 25)
Biodiversity of mycobial communities in health and onychomycosis
Sci Rep.
12:
8872
Longitudinal T-cell receptor repertoire analysis during neoadjuvant therapy of HER2-positive breast cancer
JB Gigla, E Rosati , A-C Rambow, A-L Rumpf, DO Bauerschlag,  A Franke
(2022)
Longitudinal T-cell receptor repertoire analysis during neoadjuvant therapy of HER2-positive breast cancer
Geburtshilfe Frauenheilkd (Abstracts DGGG)
82(19):
e72
The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccination
Carina Saggau  Gabriela Rios Martini, Elisa Rosati, Silja Meise, Berith Messner, Ann-Kristin Kamps, Nicole Bekel, Johannes Gigla, Ruben Rose, Mathias Voß, Ulf M Geisen, Hayley M Reid, Melike Sümbül, Florian Tran, Dennis K Berner, Yascha Khodamoradi, Maria J G T Vehreschild, Oliver Cornely, Philipp Koehler, Andi Krumbholz, Helmut Fickenscher, Oliver Kreuzer, Claudia Schreiber, Andre Franke, Stefan Schreiber, Bimba Hoyer, Alexander Scheffold, Petra Bacher
(2022 Oct. 11)
The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccination
Immunity
55(10):
1924-1939
Network-based quantitative trait linkage analysis of microbiome composition in inflammatory bowel disease families
Arunabh Sharma, Olaf Junge, Silke Szymczak, Malte Christoph Rühlemann, Janna Enderle, Stefan Schreiber , Matthias Laudes, Andre Franke, Wolfgang Lieb, Michael Krawczak, Astrid Dempfle
(2023 Ja 23)
Network-based quantitative trait linkage analysis of microbiome composition in inflammatory bowel disease families
Front Genet
eCollection 2023:
14:1048312
Impact of diet and host genetics on the murine intestinal mycobiome
Yask Gupta # , Anna Lara Ernst # , Artem Vorobyev # , Foteini Beltsiou, Detlef Zillikens, Katja Bieber, Simone Sanna-Cherchi, Angela M Christiano, Christian D Sadik, Ralf J Ludwig #, Tanya Sezin # 
(2023 Feb 14)
Impact of diet and host genetics on the murine intestinal mycobiome
Nat Commun
14(1):
834
Fibrosis and Inflammation in Inflammatory Bowel Disease-More Than 2 Sides of the Same Coin? Lina Welz 1, Konrad Aden 2
Lina Welz, Konrad Aden
(2023 Jan)
Fibrosis and Inflammation in Inflammatory Bowel Disease-More Than 2 Sides of the Same Coin? Lina Welz 1, Konrad Aden 2
Gastroenterology
164(1):
19-21
DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon
Antonella Fazio #, Dora Bordoni #, Jan W P Kuiper, Saskia Weber-Stiehl, Stephanie T Stengel, Philipp Arnold, David Ellinghaus, Go Ito, Florian Tran, Berith Messner, Anna Henning, Joana P Bernardes, Robert Häsler, Anne Luzius, Simon Imm, Finn Hinrichsen, Andre Franke, Samuel Huber, Susanna Nikolaus, Konrad Aden, Stefan Schreiber, Felix Sommer, Gioacchino Natoli, Neha Mishra, Philip Rosenstiel
(2022)
DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon
Nat Commun
13(1):
6266
The role of cGAS/STING in intestinal immunity
Felix Wottawa, Dora Bordoni, Nathan Baran, Philip Rosenstiel, Konrad Aden 
(2021 April)
The role of cGAS/STING in intestinal immunity
 Eur J Immunol
51(4):
785-797
Effects of lifestyle and associated diseases on serum CC16 suggest complex interactions among metabolism, heart and lungs
Nathalie Rohmann, Paula Stürmer, Corinna Geisler, Kristina Schlicht, Carina Knappe, Katharina Hartmann, Kathrin Türk, Tim Hollstein, Alexia Beckmann, Anna K Seoudy, Ulla Becker, Perdita Wietzke-Braun, Ute Settgast, Florian Tran, Philip Rosenstiel, Jan H Beckmann, Witigo von Schönfels, Stephan Seifert, Jan Heyckendorf, Andre Franke, Stefan Schreiber, Dominik M Schulte, Matthias Laudes
(2023 Jun 16)
Effects of lifestyle and associated diseases on serum CC16 suggest complex interactions among metabolism, heart and lungs
J Adv Res
online ahead of print:
S2090-1232(23)00168-6.
BMI, Alcohol Consumption and Gut Microbiome Species Richness Are Related to Structural and Functional Neurological Abnormalities
Corinna Geisler, Jil Pankoke, Kristina Schlicht, Carina Knappe, Nathalie Rohmann, Katharina Hartmann, Ute Settgast, Kathrin Türk, Anna Katharina Seoudy , Andre Franke, Stefan Schreiber, Dominik M Schulte, Matthias Laudes
(2021, Oct 23)
BMI, Alcohol Consumption and Gut Microbiome Species Richness Are Related to Structural and Functional Neurological Abnormalities
Nutrients
13(11):
3743
BMI, Alcohol Consumption and Gut Microbiome Species Richness Are Related to Structural and Functional Neurological Abnormalities
Corinna Geisler, Jil Pankoke, Kristina Schlicht, Carina Knappe, Nathalie Rohmann, Katharina Hartmann, Ute Settgast, Kathrin Türk, Anna Katharina Seoudy, Andre Franke, Stefan Schreiber, Dominik M Schulte, Matthias Laudes 
(2021 Oct 23)
BMI, Alcohol Consumption and Gut Microbiome Species Richness Are Related to Structural and Functional Neurological Abnormalities
Nutrients
13(11):
3743
A dietary carbohydrate - gut Parasutterella - human fatty acid biosynthesis metabolic axis in obesity and type 2 diabetes
Lea Henneke, Kristina Schlicht, Nadia A Andreani , Tim Hollstein, Tobias Demetrowitsch, Carina Knappe, Katharina Hartmann, Julia Jensen-Kroll, Nathalie Rohmann, Daniela Pohlschneider, Corinna Geisler, Dominik M Schulte 1, Ute Settgast, Kathrin Türk, Johannes Zimmermann, Christoph Kaleta, John F Baines, Jane Shearer, Shrushti Shah, Grace Shen-Tu, Karin Schwarz, Andre Franke, Stefan Schreiber, Matthias Laudes 
(2022 April 18)
A dietary carbohydrate - gut Parasutterella - human fatty acid biosynthesis metabolic axis in obesity and type 2 diabetes
Gut Microbes
14(1):
2057778
Vitamin C and Omega-3 Fatty Acid Intake Is Associated with Human Periodontitis-A Nested Case-Control Study
Louisa Mewes, Carina Knappe, Christian Graetz, Juliane Wagner , Tobias J Demetrowitsch, Julia Jensen-Kroll, Karim Mohamed Fawzy El-Sayed, Karin Schwarz, Christof E Dörfer, Stefan Schreiber , Matthias Laudes, Dominik M Schulte
(2022 May 5)
Vitamin C and Omega-3 Fatty Acid Intake Is Associated with Human Periodontitis-A Nested Case-Control Study
Nutrients
14(9):
1939
Cohort profile: the Food Chain Plus (FoCus) cohort
Corinna Geisler, Kristina Schlicht, Carina Knappe, Nathalie Rohmann, Katharina Hartmann, Kathrin Türk, Ute Settgast, Dominik M Schulte , Tobias Demetrowitsch, Julia Jensen-Kroll, Alina Pisarevskaja, Fynn Brix, Bärbel Gruber, Gerald Rimbach, Frank Döring, Philip Rosenstiel, Andre Franke, Stefan Schreiber, Christian H C A Henning, Wolfgang Lieb, Ute Nöthlings, Karin Schwarz, Matthias Laudes 
(2022 Oct)
Cohort profile: the Food Chain Plus (FoCus) cohort
Eur J Epidemiol
37(10):
Dipeptidylpeptidase (DPP)-4 inhibitor therapy increases circulating levels of anti-inflammatory soluble frizzle receptor protein (sFRP)-5 which is decreased in severe COVID-19 disease
Juliane Brandes #, Isabelle Zobel #, Nathalie Rohmann, Kristina Schlicht, Corinna Geisler, Katharina Hartmann, Kathrin Türk, Witigo von Schönfels, Jan Beckmann, Florian Tran, Matthias Laudes 
(2022 Sept. 2)
Dipeptidylpeptidase (DPP)-4 inhibitor therapy increases circulating levels of anti-inflammatory soluble frizzle receptor protein (sFRP)-5 which is decreased in severe COVID-19 disease
Sci Rep
12(1):
14935
A Prospective Analysis of the Metyrapone Short Test Using Targeted and Untargeted Metabolomics
Anna Katharina Seoudy , Kristina Schlicht, Alexandra Kulle, Tobias Demetrowitsch, Alexia Beckmann, Corinna Geisler, Kathrin Türk, Nathalie Rohmann, Katharina Hartmann, Juliane Brandes, Dominik M Schulte, Stefan Schreiber, Karin Schwarz, Paul-Martin Holterhus, Matthias Laudes 
(2023)
A Prospective Analysis of the Metyrapone Short Test Using Targeted and Untargeted Metabolomics
Neuroendocrinology
113(7):
770-784
PREPRINT: Predicting Peptide HLA-II Presentation Using Immunopeptidomics, Transcriptomics and Deep Multimodal Learning
Hesham ElAbd, Mareike Wendorff, Tomas Koudelka, Christian Hentschker, Ann-Kristin Kamps, Christoph Prieß, Lars Wienbrandt, Frauke Degenhardt, Tim A. Steiert, Petra Bacher, Piyush Mathur, David Ellinghaus, Uwe Völker, Andreas Tholey, Tobias L. Lenz, Andre Franke
(PREPRINT: 2022 Sept. 20)
PREPRINT: Predicting Peptide HLA-II Presentation Using Immunopeptidomics, Transcriptomics and Deep Multimodal Learning
bioRxiv
PREPRINT: VCF2Prot: An Efficient and Parallel Tool for Generating Personalized Proteomes from VCF Files
Hesham ElAbd, Frauke Degenhardt, Tobias L. Lenz, Andre Franke, Mareike Wendorff
(PREPRINT: 2022, Jan 21)
PREPRINT: VCF2Prot: An Efficient and Parallel Tool for Generating Personalized Proteomes from VCF Files
bioRxiv
PREPRINT: Genome-wide analysis of individual coding variants and HLA-II-associated self-immunopeptidomes in ulcerative colitis
Mareike Wendorff, Hesham ElAbd, Frauke Degenhardt, Marc Höppner, Florian Uellendahl-Werth, Eike M. Wacker, Lars Wienbrandt, Simonas Juzenas, Regeneron Genetic Center, Tomas Koudelka, David Ellinghaus, Petra Bacher, Andreas Tholey, Matthias Laudes, Malte Ziemann, Bernd Bokemeyer, Stefan Schreiber, Tobias L. Lenz, Andre Franke
(PREPRINT: 2023 March 22)
PREPRINT:Genome-wide analysis of individual coding variants and HLA-II-associated self-immunopeptidomes in ulcerative colitis
medRxiv
NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia
Priyadarshini Kachroo, Silke Szymczak , Femke-Anouska Heinsen, Michael Forster, Jörn Bethune, Georg Hemmrich-Stanisak, Lewis Baker, Martin Schrappe, Martin Stanulla, Andre Franke
(2018 Feb. Epub 2018 Jan 15.)
NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia
Epigenomics .
10 (2):
133-147
High-throughput method for the hybridisation-based targeted enrichment of long genomic fragments for PacBio third-generation sequencing
Tim Alexander Steiert, Janina Fuß, Simonas Juzenas, Michael Wittig, Marc Patrick Hoeppner, Melanie Vollstedt, Greta Varkalaite, Hesham ElAbd, Christian Brockmann, Siegfried Görg, Christoph Gassner, Michael Forster, Andre Franke
(2022 Jul 13. eCollection 2022 Sep.)
High-throughput method for the hybridisation-based targeted enrichment of long genomic fragments for PacBio third-generation sequencing
NAR Genom Bioinform .
4(3):
lqac051
Challenges and opportunities in analyzing and modeling peptide presentation by HLA-II proteins
Hesham ElAbd, Petra Bacher, Andreas Tholey, Tobias L Lenz, Andre Franke
(2023 Mar 29.eCollection 2023.)
Challenges and opportunities in analyzing and modeling peptide presentation by HLA-II proteins
Front Immunol .
14:
1107266
Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles
Frauke Degenhardt, Mareike Wendorff , Michael Wittig, Eva Ellinghaus, Lisa W Datta, John Schembri, Siew C Ng, Elisa Rosati, Matthias Hübenthal, David Ellinghaus, Eun Suk Jung, Wolfgang Lieb, Shifteh Abedian, Reza Malekzadeh, Jae Hee Cheon, Pierre Ellul, Ajit Sood, Vandana Midha, B K Thelma, Sunny H Wong, Stefan Schreiber, Keiko Yamazaki, Michiaki Kubo, Gabrielle Boucher, John D Rioux, Tobias L Lenz, Steven R Brant , Andre Franke
(2019 Jun. 15)
Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles
Hum Mol Genet .
28(12):
2078-2092
Amino acid encoding for deep learning applications
Hesham ElAbd, Yana Bromberg , Adrienne Hoarfrost, Tobias Lenz, Andre Franke, Mareike Wendorff
(2020 Jun. 09)
Amino acid encoding for deep learning applications
BMC Bioinformatics
21(1):
235
Unbiased Characterization of Peptide-HLA Class II Interactions Based on Large-Scale Peptide Microarrays; Assessment of the Impact on HLA Class II Ligand and Epitope Prediction
Mareike Wendorff, Heli M Garcia Alvarez, Thomas Østerbye, Hesham ElAbd, Elisa Rosati, Frauke Degenhardt , Søren Buus , Andre Franke, Morten Nielsen
(2020 Aug. 5, eCollection 2020)
Unbiased Characterization of Peptide-HLA Class II Interactions Based on Large-Scale Peptide Microarrays; Assessment of the Impact on HLA Class II Ligand and Epitope Prediction
Front Immunol .
11:
1705
Genomewide Association Study of Severe Covid-19 with Respiratory Failure
Severe Covid-19 GWAS Group; David Ellinghaus, Frauke Degenhardt, Luis Bujanda, .... , Jan Kässens, Sandra May, Mareike Wendorff , Lars Wienbrandt, Florian Uellendahl-Werth, ..., Georg Hemmrich-Stanisak , ..., Hesham ElAbd, Ilaria My , ..., Malte C Rühlemann , ..., Martin Schulzky , ..., Michael Wittig, ..., Simonas Juzenas , ..., Tobias L Lenz , ..., Mauro D'Amato , Stefano Duga , Jesus M Banales , Johannes R Hov , Trine Folseraas , Luca Valenti , Andre Franke, Tom H Karlsen
(2020 Oct. 15, Epub 2020 Jun 17)
Genomewide Association Study of Severe Covid-19 with Respiratory Failure
N Engl J Med .
383(16):
1522-1534
Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations
Degenhardt F, Mayr G, Wendorff M, Boucher G, Ellinghaus E, Ellinghaus D, ElAbd H, Rosati E, Hübenthal M, Juzenas S, Abedian S, Vahedi H, Thelma BK, Yang SK, Ye BD, Cheon JH, Datta LW, Daryani NE, Ellul P, Esaki M, Fuyuno Y, McGovern DPB, Haritunians T, Hong M, Juyal G, Jung ES, Kubo M, Kugathasan S, Lenz TL, Leslie S, Malekzadeh R, Midha V, Motyer A, Ng SC, Okou DT, Raychaudhuri S, Schembri J, Schreiber S, Song K, Sood A, Takahashi A, Torres EA, Umeno J, Alizadeh BZ, Weersma RK, Wong SH, Yamazaki K, Karlsen TH, Rioux JD, Brant SR; MAAIS Recruitment Center; Franke A; International IBD Genetics Consortium.
(2021 Apr 27)
Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations
Hum Mol Genet .
30(5):
356-369
Immunopeptidomics toolkit library (IPTK): a python-based modular toolbox for analyzing immunopeptidomics data
Hesham ElAbd, Frauke Degenhardt, Tomas Koudelka, Ann-Kristin Kamps, Andreas Tholey, Petra Bacher, Tobias L Lenz, Andre Franke, Mareike Wendorff
(2021)
Immunopeptidomics toolkit library (IPTK): a python-based modular toolbox for analyzing immunopeptidomics data
BMC Bioinformatics
22(1):
405
A first update on mapping the human genetic architecture of COVID-19
COVID-19 Host Genetics Initiative
(2022)
A first update on mapping the human genetic architecture of COVID-19
Nature
Epub 2022 Aug 3:
608(7921):E1-E10.
A second update on mapping the human genetic architecture of COVID-19.
COVID-19 Host Genetics Initiative
(2023)
A second update on mapping the human genetic architecture of COVID-19.
Nature
Epub 2023 Sep 6.:
621(7977):E7-E26.
The intracellular proteome of the gut bacterium Bacteroides thetaiotaomicron is widely unaffected by a switch from glucose to sucrose as main carbohydrate source
Genth J, Kaleja P, Treitz C, Schäfer K, Graspeutner S, Rupp J, Tholey A.
(2022)
The intracellular proteome of the gut bacterium Bacteroides thetaiotaomicron is widely unaffected by a switch from glucose to sucrose as main carbohydrate source
Proteomics
Jul 29;e2200189
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H, Rühlemann MC, Arora J, Özer O, Lenning OB, Myhre R, Vadla MS, Wacker EM, Wienbrandt L, …, D'Amato M, …, Bacher P, … Tran F, …, Lenz TL, Asselta R, Cid R, Valenti L, Karlsen TH, Cáceres M, Franke A.
(2022)
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
Hum Mol Genet.
Jul 15:ddac158:
1127: Epithelial CGAS/STING Guides DNA Damage-driven Stem Cell Function and protect from Intestinal Carcinogenesis
Hang Xiang, Gabriela Rios Martini, Felix Wottawa, Joana P. Bernardes, Björn Konukiewitz, Florian Tran, Nassim H. Kakavand, Qicong Wu, Julia Kugler, Lina Welz, Philip Rosenstiel, Konrad Aden
(2022)
1127: Epithelial CGAS/STING Guides DNA Damage-driven Stem Cell Function and protect from Intestinal Carcinogenesis
Gastroenterology
May, 162:
7, Supplement; S-262
A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies
Strippel C, Herrera-Rivero M, Wendorff M, Tietz AK, Degenhardt F, Witten A, Schroeter C, Nelke C, Golombeck KS, Madlener M, Rüber T, Ernst L, Racz A, Baumgartner T, Widman G, Doppler K, Thaler F, Siebenbrodt K, Dik A, Kerin C, Räuber S, Gallus M, Kovac S, Grauer OM, Grimm A, Prüss H, Wickel J, Geis C, Lewerenz J, Goebels N, Ringelstein M, Menge T, Tackenberg B, Kellinghaus C, Bien CG, Kraft A, Zettl U, Ismail FS, Ayzenberg I, Urbanek C, Sühs KW, Tauber SC, Mues S, Körtvélyessy P, Markewitz R, Paliantonis A, Elger CE, Surges R, Sommer C, Kümpfel T, Gross CC, Lerche H, Wellmer J, Quesada CM, Then Bergh F, Wandinger KP, Becker AJ, Kunz WS, Meyer Zu Hörste G, Malter MP, Rosenow F, Wiendl H, Kuhlenbäumer G, Leypoldt F, Lieb W, Franke A, Meuth SG, Stoll M, Melzer N; German Network for Research on Autoimmune Encephalitis (GENERATE).
(2022)
A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies
Brain
Mar 28:awac119:
Ecology impacts the decrease of Spirochaetes and Prevotella in the fecal gut microbiota of urban humans
. Louise B Thingholm, Corinna Bang, Malte C Rühlemann, Annika Starke , Florian Sicks , Verena Kaspari , Anabell Jandowsky, Kai Frölich, Gabriele Ismer, Andreas Bernhard, Claudia Bombis, Barbara Struve, Philipp Rausch, Andre Franke
(2021)
Ecology impacts the decrease of Spirochaetes and Prevotella in the fecal gut microbiota of urban humans
BMC Microbiol
Oct 11;21(1):
276
Culturomics Approaches Expand the Diagnostic Accuracy for Sexually Transmitted Infections
Ellinor Anna Wolf, Hannah Clara Rettig, Mariia Lupatsii, Britta Schlüter, Kathrin Schäfer, Dirk Friedrich, Simon Graspeuntner and Jan Rupp
(2021)
Culturomics Approaches Expand the Diagnostic Accuracy for Sexually Transmitted Infections
International Journal of Molecular Sciences
Oct. 6, 22(19):
10815
Circulating sDPP-4 is Increased in Obesity and Insulin Resistance but Is Not Related to Systemic Metabolic Inflammation
Rohmann N*, Schlicht K*, Geisler C, Hollstein T, Knappe C, Krause L, Hagen S, Beckmann A, Seoudy AK, Wietzke-Braun P, Hartmann K, Schulte DM, Türk K, Beckmann J, von Schönfels W, Hägele FA, Bosy-Westphal A, Franke A, Schreiber S and Laudes M.
(2021)
Circulating sDPP-4 is Increased in Obesity and Insulin Resistance but Is Not Related to Systemic Metabolic Inflammation
J Clin Endocrinol Metab.
Jan 23; 106(2):
e592-e601
Precision Nutrition in Chronic Inflammation.
Demetrowitsch TJ, Schlicht K, Knappe C, Zimmermann J, Jensen-Kroll J, Pisarevskaja A, Brix F, Brandes J, Geisler C, Marinos G, Sommer F, Schulte DM, Kaleta C, Andersen V, Laudes M, Schwarz K and Waschina S.
(2020)
Precision Nutrition in Chronic Inflammation.
Front. Immunol.
Nov; 11:
587895
Genomewide association study of psoriasis in Egyptian population
Bejaoui Y, Witte M, …, Wendorff M, Ellinghaus E, Franke A, Ibrahim SM
(2019)
Genomewide association study of psoriasis in Egyptian population
Exp. Dermatol.
May;28(5):
623-627
Increased phosphorylation of eNOS in nasal polyps of chronic rhinosinusitis patients can be diminished by 1,8-cineol.
Koennecke M, Benecke F, Masche A, Linke R, Bruchhage KL, Pries R, Klimek L, Wollenberg B.
(2018)
Increased phosphorylation of eNOS in nasal polyps of chronic rhinosinusitis patients can be diminished by 1,8-cineol.
Nitric Oxide.
Aug 1; 78:
89-94
Nuclear factor E2 related factor-2 differentially impacts on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells - a condition favouring metabolic symbiosis between colorectal cancer and stromal cells
Diehl K, Dinges LA, Helm O, Ammar N, Plundrich D, Arlt A, Röcken C, Sebens S, Schäfer H.
(2018)
Nuclear factor E2 related factor-2 differentially impacts on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells - a condition favouring metabolic symbiosis between colorectal cancer and stromal cells
Oncogene
Jan 4;37(1):
39-51
Regulated proteolysis as an element of ER stress and autophagy: Implications for intestinal inflammation
Stengel S, Messner B, Falk-Paulsen M, Sommer N, Rosenstiel P.
(2017)
Regulated proteolysis as an element of ER stress and autophagy: Implications for intestinal inflammation
Biochim Biophys Acta Mol Cell Res.
1864(11 Pt B):
2183-2190
Detailed stratified GWAS analysis for severe COVID-19 in four European populations.
Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H, Rühlemann MC, Arora J, Özer O, Lenning OB, Myhre R, Vadla MS, Wacker EM, Wienbrandt L, …, D'Amato M, …, Bacher P, … Tran F, …, Lenz TL, Asselta R, Cid R, Valenti L, Karlsen TH, Cáceres M, Franke A.
(2022)
Detailed stratified GWAS analysis for severe COVID-19 in four European populations.
Hum Mol Genet.
Jul 15:ddac158:
Distinct metabolite profile in pemphigus vulgaris
Katharina Boch, Arunabh Sharma, Julica Folberth, Detlef Zillikens, Enno Schmidt, Katja Bieber, Markus Schwaninger , Ralf J Ludwig, Astrid Dempfle.
(2022)
Distinct metabolite profile in pemphigus vulgaris
J Invest Dermatol.
Jun 16; S0022-202X(22)01546-9:
Characterization of the skin microbiota in bullous pemphigoid patients and controls reveals novel microbial indicators of disease
Meriem Belheouane, Britt M. Hermes, Nina Van Beek, Sandrine Benoit, Philippe Bernard, Kossara Drenovska, Sascha Gerdes, Regine Gläser, Matthias Goebeler, Claudia Günther, Anabelle von Georg, Christoph M. Hammers, Maike M. Holtsche, Bernhard Homey, Orsolya N. Horváth, Franziska Hübner, Beke Linnemann, Pascal Joly, Dalma Márton, Aikaterini Patsatsi, Claudia Pföhler, Miklós Sárdy, Laura Huilaja, Snejina Vassileva, Detlef Zillikens, Saleh Ibrahim, Christian D. Sadik, Enno Schmidt, John F. Baines.
(2022)
Characterization of the skin microbiota in bullous pemphigoid patients and controls reveals novel microbial indicators of disease
J Adv Res.
Apr. 4; S2090-1232(22)00081-9:
Linkage analysis identifies novel genetic modifiers of microbiome traits in families with inflammatory bowel disease
Sharma, A., Szymczak, S., Rühlemann, M., Freitag-Wolf, S., Knecht, C., Enderle, J., Schreiber S., Franke A., Lieb W., Krawczak M. & Dempfle, A.
(2022)
Linkage analysis identifies novel genetic modifiers of microbiome traits in families with inflammatory bowel disease
Gut Microbes
Feb. 06 published online; 14(1), 2024415:
A novel unconventional T cell population enriched in Crohn’s disease
Elisa Rosati, Gabriela Rios Martini, Frauke Degenhardt, Mareike Wendorff, Mikhail V. Pogorelyy, Anastasia A. Minervina, Gabriele Mayr, Antonella Fazio, C. Marie Dowds, Charlotte Hauser, Florian Tran, Maria A. Salnikova, Charlot Jaeckel, Johannes B. Gigla, Sanaz S. Sabet, Konrad Aden, Matthias Hübenthal, Esther Schiminsky, Stefan Schreiber, Philip C. Rosenstiel, Alexander Scheffold, Wolfgang Lieb, Bernd Bokemeyer, Alexander Hendricks, Clemens Schafmayer, Jan-Hendrick Egberts, Ilgar Z. Mamedov*, Petra Bacher* & Andre Franke*
(2022)
A novel unconventional T cell population enriched in Crohn’s disease
Gut
March 09, online:
gutjnl-2021-325373
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Mast cell-deficient mice Mcpt5Cre/Dicerfl/fl redefine the role of mast cells in experimental bullous pemphigoid in skin health and disease.
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Nutritional Targeting of the Microbiome as Potential Therapy for Malnutrition and Chronic Inflammation
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Nutritional Targeting of the Microbiome as Potential Therapy for Malnutrition and Chronic Inflammation
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Genetic control of psoriasis is relatively distinct from that of metabolic syndrome and coronary artery disease
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(2013)
Genetic control of psoriasis is relatively distinct from that of metabolic syndrome and coronary artery disease
John Wiley & Sons A/S. Published by John Wiley & Sons Ltd, Experimental Dermatology
Aug; 22(8):
552-553